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| [00:04.91]54) Anti-sense Technology [00:10.55]Research scientists have reported success in using an experimental method [00:17.97]called anti-sense technology to treat people with cancer. [00:23.41]For years, researchers have tested anti-sense technology to treat cancer in humans. [00:30.82]But thisis the first time some cancer patients have improved after getting the treatment. [00:37.38]The findings were reported at the yearly meeting of the American Association for Cancer Research. [00:45.79]The conference was held last month in San Francisco, California. [00:52.19]Cancers result from mistakes in genetic information. [00:57.99]Some genes produce large amounts of proteins that help cancers grow. [01:04.55]The experimental treatment targets one of these genes, known as the B-C-L-Two gene. [01:13.20]In some cancer patients, the B-C-L-Two gene produces a protein that protects cancer tumors from traditional anti-cancer drugs. [01:24.87]The antisense treatment prevents the gene from acting. [01:29.70]As a result,the drugs are able to attack cancer tumors. [01:34.88]In the new study, researchers at the University of Vienna in Austria used an anti-sense drug. [01:43.78]The drug was developed by Genta Incorporated,a company based in the American city of Lexington,Massachusetts. [01:52.25]The researchers gave the anti-sense drug and the anticancer drug dacarbazine to fourteen people with advanced melanoma. [02:03.87]Melanoma is a deadly kind of skin cancer. [02:07.79]Earlier, dacarbazine and other anti-cancer treatments had failed to help most of the patients. [02:15.39]However, the combination antisense treatment helped six of the fourteen patients. [02:22.79]There was some improvement in five patients. [02:26.94]In one patient,the cancer disappeared completely. [02:31.48]The researchers said they believe the side effects of the treatment are acceptable. [02:38.72]Some patients experienced changes in skin color,higher than normal body temperature and temporary liver problems |
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